The most reliable new midsize SUVs in 2025

Finding a reliable midsize SUV in 2025 doesn’t have to mean spending a fortune. With new car prices near record highs, buyers want vehicles that last as long as possible while delivering solid performance and comfort.

Midsize SUVs remain one of the most popular segments in the U.S., with options ranging from three-row family haulers to rugged off-roaders. Based on new research from iSeeCars, which analyzed prices and life expectancy of over 3.8 million new vehicles, these are the best new midsize SUVs for the money in 2025.

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1. Toyota Highlander

2025 Toyota Highlander

Toyota

The Toyota Highlander is the most reliable midsize SUV for the money in 2025. With an average list price of $48,481 and an expected lifespan of 13.9 years, it costs just $3,489 per year to own, significantly below the segment average. Known for its strong resale value and solid build quality, the Highlander continues to be a top choice for families who need space and reliability.

2. Toyota 4Runner

2025 Toyota 4Runner TRDPro

Toyota

For buyers who prioritize durability, the Toyota 4Runner remains one of the most rugged and long-lasting SUVs on the market. Its body-on-frame construction and off-road prowess contribute to its 14.6-year lifespan, one of the highest in this category. The 4Runner’s $52,056 price tag results in a $3,557 cost per year, making it a standout choice for adventure seekers who also want long-term reliability.

Related: Is the 2025 Corvette Z06 worth $112,100?

3. Toyota Highlander Hybrid

2025 Toyota Highlander Hybrid

Toyota

The hybrid version of the Toyota Highlander offers the same expected 13.9-year lifespan as its gasoline-powered counterpart but with improved fuel efficiency. With an average list price of $52,565, its cost per year of ownership comes in at $3,773—still well below the segment average. For those looking to save on gas while maximizing longevity, the Highlander Hybrid is a smart buy.

4. Lexus RX 350h

2024 Lexus RX 350h

Lexus

Luxury and longevity don’t always go hand in hand, but the Lexus RX 350h proves otherwise. This hybrid SUV boasts an impressive 15.7-year lifespan, the longest on this list, and an average price of $60,857. That translates to a $3,865 cost per year—less than many mainstream SUVs.

5. Lexus RX 350

2024 Lexus RX 350

Lexus

For those who prefer a traditional gasoline engine, the Lexus RX 350 offers similar longevity to its hybrid sibling at 14.9 years. Priced at $57,838, its cost per year comes out to $3,892. With Lexus’ reputation for durability and a plush interior packed with technology, the RX 350 is a strong contender for luxury SUV buyers who prioritize reliability.

Related: Mercedes reportedly working on “baby G-Wagen” variant

6. Jeep Wrangler

2025 Jeep Wrangler

Jeep

The Jeep Wrangler may be best known for its off-road capabilities, but it’s also a long-lasting SUV. With an expected lifespan of 14.4 years and an average price of $56,252, its cost per year of ownership is $3,894. While the Wrangler’s ride quality and refinement lag behind more road-friendly SUVs, its ability to tackle tough terrain and hold its value makes it a great choice for adventure lovers.

7. Nissan Murano

2025 Nissan Murano

Nissan

The Nissan Murano might not be the flashiest SUV, but it delivers on reliability and value. With an 11.6-year lifespan and a price tag of $45,205, it costs $3,912 per year to own. Known for its smooth ride and upscale interior, the Murano appeals to those seeking a comfortable midsize SUV that won’t break the bank.

8. Honda Pilot

2025 Honda Pilot

Honda

Honda’s three-row Pilot is a family favorite, offering a solid blend of space, technology, and dependability. With an expected lifespan of 12.1 years and an average price of $49,817, it costs $4,131 per year to own—slightly higher than some competitors but still below the segment average. The Pilot remains a top pick for those needing extra passenger and cargo space without sacrificing longevity.

Related: Thinking about buying a Toyota Prius? Here are other top choices to consider

9. INFINITI QX60

2025 INFINITI QX60

INFINITI

For those looking at luxury brands, the INFINITI QX60 offers a respectable 14.7-year lifespan, which helps justify its $61,286 price tag. That results in a $4,173 cost per year—higher than some mainstream models but still a good value for a luxury SUV.

10. Nissan Pathfinder

2025 Nissan Pathfinder Rock Creek

Nissan

The Nissan Pathfinder is another strong option in the three-row SUV segment, boasting an 11-year lifespan. With an average price of $46,975, it costs $4,273 per year to own. While not as long-lasting as some competitors, the Pathfinder remains a practical choice for families needing a spacious SUV with decent longevity.

11. Hyundai Santa Fe

2025 Hyundai Sante Fe Hybrid

Hyundai

Hyundai’s Santa Fe earns a spot on this list thanks to its affordability. Priced at $43,999 with an expected lifespan of 10.2 years, it costs $4,309 per year to own. While its longevity isn’t as strong as some rivals, the Santa Fe’s warranty coverage and solid feature set make it a reliable, budget-friendly option.

Related: Thinking about buying a 2025 Hyundai Santa Fe? Here are other top choices to consider

12. Lexus RX 500h

2025 Lexus RX 500h Performance Black Line Special Edition

Lexus

The Lexus RX 500h sits at the top of the RX lineup, offering both hybrid efficiency and Lexus’ well-known reliability. With an impressive 15.7-year lifespan and a steep $72,155 price, it costs $4,583 per year—just under the segment average. For buyers willing to invest in a luxury hybrid with a long road ahead, the RX 500h delivers excellent value.

Final thoughts

Midsize SUVs remain a smart choice for buyers seeking a balance between practicality, comfort, and reliability. While prices in this segment vary widely, the models listed here provide the best return on investment in terms of longevity. 

Whether opting for a rugged off-roader like the 4Runner, a premium SUV like the Lexus RX, or a family-friendly staple like the Highlander, buyers in 2025 have strong options that will last well beyond the average vehicle lifespan.

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